The more lipid soluble the barbiturate, the more rapidly it penetrates all tissues of the body. Barbiturates are bound to plasma and tissue proteins to a varying degree with the degree of binding increasing directly as a function of lipid solubility.
Durante convulsive states, dosage of NEMBUTAL Sodium Solution should be kept to a minimum to avoid compounding the depression which may follow convulsions. The injection must be made slowly with due regard to the time required for the drug to penetrate the blood-brain barrier.
Screen patients for contraindications and potential risk factors before initiating pentobarbital therapy.
Seizures: Symptoms and Types Seizures occur when there is an abnormal burst of electrical activity Con the brain and are divided into two categories: generalized and partial.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
However, the use of barbiturates as sedatives Per the postoperative surgical period and as adjuncts to cancer chemotherapy is well established.
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Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.
Per mezzo di general, quota selection for an elderly more info patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.
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The concomitant use of alcohol or other CNS depressants may produce additive CNS depressant effects.
Pentobarbital read more can cause drowsiness and impair mental and physical abilities. Avoid hazardous activities such as driving and operating heavy machinery.